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JA Performance Peptides
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5-Amino-1MQ 5mg
Body Composition

5-Amino-1MQ

5mg · Lyophilized Powder

VIAL SIZE

$50.00 CAD

5-Amino-1MQ is a selective, cell-permeable inhibitor of Nicotinamide N-methyltransferase (NNMT) — the cytosolic enzyme that metabolises nicotinamide using S-adenosylmethionine, competing with NAD+ biosynthesis and methylation reactions. By blocking NNMT, 5-Amino-1MQ may restore cellular NAD+ availability, activate SIRT1 longevity pathways, and enhance fat oxidation via improved metabolic efficiency. Preclinical models demonstrate increased thermogenesis, reduction in fat cell size, and improved insulin sensitivity.

Research Applications

NNMT inhibition for intracellular NAD+ preservation and restoration
SIRT1 pathway activation for metabolic and longevity research
Fat oxidation and thermogenesis enhancement research
Insulin sensitivity and glucose metabolism research
Lean mass preservation during caloric deficit research protocols
Synergistic research with NAD+ precursors (NMN, NR)
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Commonly paired: Metabolic Core

NAD+, MOTS-c and 5-Amino-1MQ are commonly studied together for mitochondrial function and metabolic research.

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All products sold by JA Performance Peptides are intended strictly for laboratory research purposes and are not approved for human consumption, veterinary use, or therapeutic application. Not for human use.

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Frequently Asked Questions — 5-Amino-1MQ

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